The Lewis Integrative Science Building (LISB) is home to research clusters centered on interdisciplinary and integrative research missions. The building houses biologists, chemists, psychologists, neurologists, computer scientists, and other researchers working alongside one another to tackle challenges related to the brain and its functions. The building also houses space for solar technology and green chemistry research. Most of the dry labs (mainly the bioinformatics and computational biology research labs) support non-invasive cognitive studies focused on how the brain processes and remembers information. The majority of the wet labs house systems neuroscience and cell biology research labs.
Designed with sustainability in mind, the LEED Platinum-certified building uses 58 percent less energy than conventionally designed buildings of similar size and function. Energy savings features include natural ventilation in non-lab spaces, solar shading, daylight harvesting, night flush cooling, variable flow chemical fume hoods with automatic sashes that close when not in use, and the extraction of heat from an adjacent utility tunnel. To reduce usage of potable water, LISB reclaims reverse osmosis treated water from a neighboring zebra fish research facility and uses this water to flush all urinals and toilets.